Publications
77.
Atroposelective Arene-Forming Wittig Reaction by Phosphorus PIII/PV=O Redox Catalysis
K. Jana, Z. Zhao, J. Musies, C. Sparr*
Angew. Chem. Int. Ed. 2024, 63, e202408159.
76.
Atroposelective catalysis
T. A. Schmidt,+ V. Hutskalova,+ C. Sparr*
Nat. Rev. Chem. 2024, 8, 497. (+ denotes equal contributions). SharedIt Link
75.
Decarboxylative Nickel- and Photoredox-Catalyzed Aminocarbonylation of (Hetero)Aryl Bromides
V. Hutskalova, F. Bou Hamdan,* C. Sparr*
Org. Lett. 2024, 26, 2768. Special Issue: Organic Chemistry Driven by Academic-Industrial Collaborations.
74.
Catalyst control over pentavalent stereocentres
A. Budeev, J. Dong, D. Häussinger, C. Sparr*
Nat. Commun. 2023, 14, 8013.
73.
Artificial Metalloenzymes for Atroposelective Metathesis
T. Vornholt,+ Z. Jončev,+ V. Sabatino, S. Panke, T. R. Ward,* C. Sparr,* M. Jeschek*
ChemCatChem 2023, 15, e202301113. (+ denotes equal contributions).
72.
Isoacridone dyes with parallel reactivity from both singlet and triplet excited states for biphotonic catalysis and upconversion
B. Pfund,+ V. Hutskalova,+ C. Sparr,* O. S. Wenger*
Chem. Sci. 2023, 14, 11180. (+ denotes equal contributions).
71.
Diastereodivergent Catalysis
D. Moser,+ T. A. Schmidt,+ C. Sparr*
JACS Au 2023, 3, 2612. (+ denotes equal contributions). Invited Perspective Article
70.
Atroposelective PIII/PV=O Redox Catalysis for the Isoquinoline-Forming Staudinger–aza-Wittig Reaction
D. Moser, K. Jana, C. Sparr*
Angew. Chem. Int. Ed. 2023, 62, e202309053. Selected as VIP
69.
Catalyst Control over Threefold Stereogenicity: Selective Synthesis of Atropisomeric Sulfones with Stereogenic C–S Axes
T. A. Schmidt, S. Schumann, A. Ostertag, C. Sparr*
Angew. Chem. Int. Ed. 2023, 62, e202302084.
68.
Control over Stereogenic N–N Axes by Pd-catalyzed 5-endo-Hydroaminocyclizations
V. Hutskalova, C. Sparr*
Synthesis 2023, 55, 1770. Special Issue dedicated to Prof. Cristina Nevado, Recipient of the 2021 Dr. Margaret Faul Women in Chemistry Award
67.
Atroposelective Arene-Forming Alkene Metathesis
Z. Jončev, C. Sparr*
Angew. Chem. Int. Ed. 2022, 61, e202211168. Preprint deposited on ChemRxiv.
66.
o-Quinodimethane Atropisomers: Enantioselective Synthesis and Stereospecific Transformation
J. Dong,+ A. Ostertag,+ C. Sparr*
Angew. Chem. Int. Ed. 2022, 61, e202212627. (+ denotes equal contributions).
65.
Photocatalytic deracemisation of cobalt(III) complexes with fourfold stereogenicity
T. A. Schmidt, C. Sparr*
Chem. Comm. 2022, 58, 12172. Pioneering Investigator 2022
64.
X-Ray Crystallographic Studies of Quasi-Racemates for Absolute Configuration Determinations
X. Wu, J. Malinčík, A. Prescimone, C. Sparr*
Helv. Chim. Acta 2022, 105, e202200117. Special Issue in memory of Professor Jack D. Dunitz
63.
Synthesis of Diarylaminoacridinium Photocatalysts by Halogen-Metal Exchange Combined with Directed ortho Metalations
M. Jakobi, B. Zilate, C. Sparr*
Adv. Synth. Catal. 2022, 364, 3384. Selected as VIP. Special Issue Honoring Prof. Andreas Pfaltz
62.
Streamlined Synthesis of Aminoacridinium Photocatalysts with Improved Photostability
M. Jakobi, C. Sparr*
Org. Process Res. Dev. 2022, 26, 2756. (invited)
61.
Synthesis of Atropisomeric Two-Axis Systems by the Catalyst- Controlled syn- and anti-Selective Arene-Forming Aldol Condensation
D. Moser, C. Sparr*
Angew. Chem. Int. Ed. 2022, 61, e202202548.
60.
Synthesis and Applications of Acridinium Salts
V. Hutskalova, C. Sparr*
Science of Synthesis 2022, 15.9.4.
59.
Retrosynthetic polyketide disconnections for unnatural aromatics
X. Wu, C. Sparr*
Trends Chem. 2022, 4, 367.
58.
Stereoselective Synthesis of Atropisomeric Acridinium Salts by the Catalyst-Controlled Cyclization of ortho-Quinone Methide Iminiums
X. Wu, C. Sparr*
Angew. Chem. Int. Ed. 2022, 61, e202201424.
57.
The Versatility of the Aryne–Imine–Aryne Coupling for the Synthesis of Acridinium Photocatalysts
V. Hutskalova, C. Sparr*
Synlett 2022, 33, 1180. Special Issue Honoring Prof. Shunichi Fukuzumi’s 70th Birthday (invited)
56.
Synthesis of Helical and Planar Extended-Phenanthridinium Salts
V. Hutskalova, A. Prescimone, C. Sparr*
Helv. Chim. Acta 2021, 104, e202100182. Special Issue for the 75th birthday of Prof. E. Peter Kündig
55.
Catalyst-Controlled Stereoselective Barton–Kellogg Olefination
T. A. Schmidt, C. Sparr*
Angew. Chem. Int. Ed. 2021, 60, 23911. Selected as VIP
54.
Aldehyde-Catalyzed Epoxidation of Unactivated Alkenes with Aqueous Hydrogen Peroxide
I. Triandafillidi, M. G. Kokotou, D. Lotter, C. Sparr,* C. G. Kokotos*
Chem. Sci. 2021, 12, 10191.
53.
Ad Hoc Adjustment of Photoredox Properties by the Late-Stage Diversification of Acridinium Photocatalysts
V. Hutskalova, C. Sparr*
Org. Lett. 2021, 23, 5143.
52.
Catalyst Control over Twofold and Higher-Order Stereogenicity by Atroposelective Arene Formation
T. A. Schmidt, C. Sparr*
Acc. Chem. Res. 2021, 54, 2764.
51.
Monitoring Solid-phase Reactions in Self-assembled Monolayers by Surface-enhanced Raman Spectroscopy
D. Scherrer, D. Vogel, U. Drechsler, A. Olziersky, C. Sparr, M. Mayor, E. Lörtscher*
Angew. Chem. Int. Ed. 2021, 60, 17981.
50.
Catalyst control over sixfold stereogenicity
X. Wu,+ R. M. Witzig,+ R. Beaud, C. Fischer, D. Häussinger, C. Sparr*
Nat. Catal. 2021, 4, 457. (+ denotes equal contributions). Preprint deposited on ChemRxiv. SharedIt Link
49.
Organophotocatalytic Aerobic Oxygenation of Phenols in a Visible‐Light Continuous‐Flow Photoreactor
J. Wellauer,+ D. Miladinov,+ T. Buchholz,+ J. Schütz, R. T. Stemmler, J. A. Medlock, W. Bonrath, C. Sparr*
Chem. Eur. J. 2021, 27, 9748. (+ denotes equal contributions)
48.
Catalyst-Controlled Transannular Polyketide Cyclization Cascades: Selective Folding of Macrocyclic Polyketides
F. C. Raps, V. C. Fäseke, D. Häussinger, C. Sparr*
Angew. Chem. Int. Ed. 2020, 59, 18390.
47.
Catalytic Cascade Reactions Inspired by Polyketide Biosynthesis
D. Moser, A. Castrogiovanni, D. Lotter, R. M. Witzig, V. C. Fäseke, F. C. Raps, C. Sparr*
Chimia 2020, 74, 699. New professors issue
46.
JoyaPhos: An Atropisomeric Teraryl Monophosphine Ligand
A. Castrogiovanni, D. Lotter, F. R. Bissegger, C. Sparr*
Chem.–Eur. J. 2020, 26, 9864. Young chemists special issue
45.
Polyketide Cyclizations for the Synthesis of Polyaromatics
V. C. Fäseke, F. C. Raps, C. Sparr*
Angew. Chem. Int. Ed. 2020, 59, 6975.
44.
Design and application of aminoacridinium organophotoredox catalysts
B. Zilate, C. Fischer, C. Sparr*
Chem. Commun. 2020, 56, 1767. Invited feature article
43.
Catalyst Repurposing Sequential Catalysis by Harnessing Regenerated Prolinamide Organocatalysts as Transfer Hydrogenation Ligands
F. Bourgeois, J. A. Medlock, W. Bonrath, C. Sparr*
Org. Lett. 2020, 22, 110.
42.
Modulation of Acridinium Organophotoredox Catalysts Guided by Photophysical Studies
C. Fischer,+ C. Kerzig,+ B. Zilate, O. S. Wenger,* C. Sparr*
ACS Catal. 2020, 10, 210. (+ denotes equal contributions)
41.
Synthesis of Enantioenriched Tetra-ortho-3,3′-substituted Biaryls by Small-Molecule-Catalyzed Noncanonical Polyketide Cyclizations
R. M. Witzig, C. Sparr*
Synlett 2020, 31, 13. Invited account article
40.
Shortcuts for Electron‐Transfer through the Secondary Structure of Helical Oligo‐1,2‐naphthylenes
A. Castrogiovanni,+ P. Herr,+ X. Guo, C. Larsen, C. Sparr,* O. S. Wenger*
Chem.–Eur. J. 2019, 25, 16748. (+ denotes equal contributions)
39.
Scalable Synthesis of Acridinium Catalysts for Photoredox Deuterations
B. Zilate, C. Fischer, L. Schneider, C. Sparr*
Synthesis 2019, 51, 4359. Practical Synthetic Procedure
38.
Atroposelective synthesis of tetra-ortho-substituted biaryls by catalyst-controlled non-canonical polyketide cyclizations
R. M. Witzig, V. C. Fäseke, D. Häussinger, C. Sparr*
Nat. Catal. 2019, 2, 925. SharedIt Link
37.
Interface-rich Aqueous Systems for Sustainable Chemical Synthesis
D. Kaldre, F. Gallou, C. Sparr,* M. Parmentier*
Chimia 2019, 73, 714. Invited, Sustainable Chemistry Issue
36.
A General Protocol for Robust Sonogashira Reactions in Micellar Medium
M. Jakobi, F. Gallou, C. Sparr,* M. Parmentier*
Helv. Chim. Acta 2019, 102, e1900024.
35.
Author Profile
C. Sparr*
Angew. Chem. Int. Ed. 2019, 58, 944.
34.
Cell Penetration, Herbicidal Activity, and in‐vivo‐Toxicity of Oligo‐Arginine Derivatives and of Novel Guanidinium‐Rich Compounds Derived from the Biopolymer Cyanophycin
M. Grogg, D. Hilvert, M.‐O. Ebert, A. K. Beck, D. Seebach,* F. Kurth, P. S. Dittrich, C. Sparr, S. Wittlin, M. Rottmann, P. Mäser
Helv. Chim. Acta 2018, 101, e1800112.
33.
Configurationally Stable Atropisomeric Acridinium Fluorophores
C. Fischer, C. Sparr*
Synlett 2018, 29, 2176. Special Issue in memoriam Kurt Mislow (invited)
32.
Remote Central-to-Axial Chirality Conversion: Direct Atroposelective Ester to Biaryl Transformation
A. Link, C. Sparr*
Angew. Chem. Int. Ed. 2018, 57, 7136.
31.
Catalyst-Controlled Stereodivergent Synthesis of Atropisomeric Multi-Axis Systems
D. Lotter, A. Castrogiovanni, M. Neuburger, C. Sparr*
ACS Cent. Sci. 2018, 4, 656.
30.
Synthesis of 1,5-Bifunctional Organolithium Reagents by a Double Directed ortho-Metalation: Direct Transformation of Esters into 1,8-Dimethoxy-Acridinium Salts
C. Fischer, C. Sparr*
Tetrahedron 2018, 74, 2436. Sir Derek Barton Centennial Special Issue (invited)
29.
Stereoselective Arene Formation
A. Link, C. Sparr*
Chem. Soc. Rev. 2018, 47, 3804. Emerging Investigator 2018
28.
Catalyst-Controlled Stereoselective Synthesis of Atropisomers
B. Zilate, A. Castrogiovanni, C. Sparr*
ACS Catal. 2018, 8, 2981.
27.
Diaryl Magnesium Lithium Alkoxides Derived from (Z)‐4‐(2‐Bromophenyl)but‐3‐en‐1‐ol
D. Lotter, C. Sparr*
in Encyclopedia of Reagents for Organic Synthesis, 2018.
26.
Direct Transformation of Esters into Heterocyclic Fluorophores
C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2018, 57, 2436.
25.
Stereoselective Arene-Forming Aldol Condensation: Catalyst-Controlled Synthesis of Axially Chiral Compounds
R. M. Witzig, D. Lotter, V. C. Fäseke, C. Sparr*
Chem. Eur. J. 2017, 23, 12960.
24.
Catalytic Arene-forming Aldol Condensation: Stereoselective Synthesis of Rotationally Restricted Aromatic Compounds
V. C. Fäseke, R. M. Witzig, A. Link, D. Lotter, C. Sparr*
Chimia 2017, 71, 596. Werner Prize 2017
23.
A 1,5-Bifunctional Organomagnesium Reagent for the Synthesis of Disubstituted Anthracenes and Anthrones
A. Link, C. Fischer, C. Sparr*
Synthesis 2017, 49, 397. Special issue dedicated to Prof. Dieter Enders (invited)
22.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Axially Chiral Aromatic Amides
V. C. Fäseke, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 7261.
21.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Configurationally Stable Oligo-1,2-naphthylenes
D. Lotter, M. Neuburger, M. Rickhaus, D. Häussinger, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 2920.
20.
Direct Transformation of Esters into Arenes with 1,5-Bifunctional Organomagnesium Reagents
A. Link, C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 12163.
19.
Scientific Fireworks to Celebrate the 50th Anniversary of the Bürgenstock Conference
C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 8594.
18.
Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation
A. Link, C. Sparr*
Angew. Chem. Int. Ed. 2014, 53, 5458.
Before Basel
17.
Molecular Design Exploiting a Fluorine gauche Effect as a Stereoelectronic Trigger
Y. P. Rey, L. E. Zimmer, C. Sparr, E.-M. Tanzer, W. B. Schweizer, H. M. Senn,* S. Lakhdar,* R. Gilmour*
Eur. J. Org. Chem. 2014, 1202.
16.
Syntheses, Receptor Bindings, in vivo Stabilities and Biodistributions of DOTA-Neurotensin(8–13) Derivatives Containing β-Amino Acid Residues – A Lesson about the Importance of Animal Experiments
C. Sparr, N. Purkayastha, T. Yoshinari, D. Seebach,* S. Maschauer, O. Prante,* H. Hübner, P. Gmeiner, B. Kolesinska, R. Cescato, B. Waser, J. C. Reubi
Chem. Biodiversity 2013, 10, 2101.
15.
Improved Efficacy of Fosmidomycin against Plasmodium and Mycobacterium Species by Combination with the Cell-Penetrating Peptide Octaarginine
C. Sparr, N. Purkayastha, B. Kolesinska, M. Gengenbacher, B. Amulic, K. Matuschewski, D. Seebach,* F. Kamena*
Antimicrob. Agents Chemother. 2013, 57, 4689.
14.
Synthesis of (–)-Hennoxazole A: Integrating Batch and Flow Chemistry Methods
A. Fernández, Z. G. Levine, M. Baumann, S. Sulzer-Mossé , C. Sparr, S. Schläger, A. Metzger, I. R. Baxendale, S. V. Ley*
Synlett 2013, 514.
13.
Exploiting Fluorine Conformational Effects in Organocatalyst Design: The Fluorine-Iminium Ion Gauche Effect
C. Sparr, L. E. Zimmer, R. Gilmour*
in Asymmetric Synthesis II: More Methods and Applications 2012, 117.
12.
Synthesis of Enantiomerically Enriched 3-Amino-2-oxindoles through a Palladium Mediated Asymmetric Intramolecular Arylation of α-Ketimino Amides
P. Tolstoy, S. X. Y. Lee, C. Sparr, S. V. Ley*
Org. Lett. 2012, 14, 4810.
11.
Preparation and Characterization of New C2- and C1- Symmetric Nitrogen, Oxygen, Phosphorous, and Sulfur Derivatives and Analogs of TADDOL. Part III
D. Seebach,* A. K. Beck, H.-U. Bichsel, A. Pichota, C. Sparr, R. Wünsch, W. B. Schweizer
Helv. Chim. Acta 2012, 95, 1303.
10.
1,2-Oxazine N-Oxides as Catalyst Resting States in Michael Additions of Aldehydes to Nitro Olefins Organocatalyzed by α,α-Diphenylprolinol Trimethylsilyl Ether
D. Seebach,* X. Sun, C. Sparr, M.-O. Ebert, W. B. Schweizer, A. K. Beck
Helv. Chim. Acta 2012, 95, 1064.
9.
Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design
L. E. Zimmer, C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2011, 50, 11860.
8.
Cyclopropyl Iminium Activation: Reactivity Umpolung in Enantioselective Organocatalytic Reaction Design
C. Sparr,* R. Gilmour*
Angew. Chem. Int. Ed. 2011, 50, 8391.
7.
Theoretical and X-ray Crystallographic Evidence of a Fluorine-Imine Gauche Effect: An Addendum to Dunathan’s Stereoelectronic Hypothesis
C. Sparr, E. Salamanova, W. B. Schweizer, H. M. Senn,* R. Gilmour*
Chem. Eur. J. 2011, 17, 8850.
6.
Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies
C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2010, 49, 6520.
5.
Stereochemical Models for Discussing Additions to α,β-Unsaturated Aldehydes Organocatalyzed by Diarylprolinol or Imidazolidinone Derivatives – Is There an '(E)/(Z)-Dilemma'?
D. Seebach,* R. Gilmour,* U. Groselj, G. Deniau, C. Sparr, M.-O. Ebert, A. K. Beck, L. B. McCusker, D. Sisak, T. Uchimaru
Helv. Chim. Acta 2010, 93, 603.
4.
A Concise Synthesis of (S)-2-(Fluorodiphenylmethyl)pyrrolidine: A Novel Organocatalyst for the Stereoselective Epoxidation of α,β-Unsaturated Aldehydes
C. Sparr, E.-M. Tanzer, J. Bachmann, R. Gilmour*
Synthesis 2010, 1394.
3.
Fluorinated Quinine Alkaloids: Synthesis, X-ray Structure Analysis and Antimalarial Parasite Chemotherapy
C. Bucher, C. Sparr, W. B. Schweizer, R. Gilmour*
Chem. Eur. J. 2009, 15, 7637.
2.
The Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis
C. Sparr, W. B. Schweizer, H. M. Senn, R. Gilmour*
Angew. Chem. Int. Ed. 2009, 48, 3065.
1.
Synthesis of a Novel γ-Folic Acid-Nτ-Histidine Conjugate Suitable for Labeling with 99mTc and 188Re
C. Sparr, U. Michel, R. E. Marti, C. Müller, R. Schibli, R. Moser, V. Groehn*
Synthesis 2009, 787.
Patents
10.
Manufacturing 2,3,5-Trimethylhydroquinone from a Mixture of Mesitol and 2,3,6-Trimethylphenol
T. Baldinger, W. Bonrath, A. Götzinger, U. Letinois, J. A. Medlock, J. Schütz, D. Miladinov, J. Wellauer, T. Buchholz, C. Sparr
9.
Photooxidation of 2,4,6-Trimethylphenol
W. Bonrath, T. Buchholz, T. Netscher, J. Schütz, C. Sparr
WO2022128852
8.
Photooxidation of Phenolic Compounds
W. Bonrath, J. A. Medlock, J. Schütz, J. Wellauer, D. Miladinov, T. Buchholz, C. Sparr
WO2021234080
7.
Photooxidation of 2,3,6-Trimethylphenol
W. Bonrath, J. A. Medlock, J. Schütz, J. Wellauer, D. Miladinov, T. Buchholz, C. Sparr
WO2021234078
6.
Photooxidation of 2,3,5-Trimethylphenol
W. Bonrath, J. A. Medlock, J. Schütz, J. Wellauer, D. Miladinov, T. Buchholz, C. Sparr
WO2021234077
5.
New Transition Metal Catalyst
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2021089482
4.
Stereoselective Synthesis of Enantiomerically-Enriched Pantolactone
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2019228874
3.
Synthesis of a Racemic Mixture of Pantolactone
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2019228873
2.
Small-Molecule Organic Dyes
C. Fischer, C. Sparr
WO2019057451
1.
Folate-Conjugates and Corresponding Metal-Chelate Complexes for Use in Diagnostic Imaging and Radiotherapy
V. Groehn, U. Michel, T. L. Mindt, R. Moser, C. M. Müller, R. Schibli, C. Sparr
WO2008125618