Publications

ToC

60.
Synthesis and Applications of Acridinium Salts
V. Hutskalova, C. Sparr*
Science of Synthesis 2022, 15.9.4.


59.
Retrosynthetic polyketide disconnection for unnatural aromatics
X. Wu, C. Sparr*
Trends Chem. 2022, 4, 367–370. 


ToC

57.
Synthesis of Helical and Planar Extended-Phenanthridinium Salts
V. Hutskalova, A. Prescimone, C. Sparr*
Helv. Chim. Acta 2021, 104, e202100182. Special Issue for the 75th birthday of Prof. E. Peter Kündig.


56.
Catalyst-Controlled Stereoselective Barton–Kellogg Olefination
T. A. Schmidt, C. Sparr*
Angew. Chem. Int. Ed. 2021, 60, 23911–23916. Selected as VIP 

TOC

55.
The Versatility of the Aryne–Imine–Aryne Coupling for the Synthesis of Acridinium Photocatalysts
V. Hutskalova, C. Sparr*
Synlett 2021, 32, accepted. Special Issue Honoring Prof. Shunichi Fukuzumi’s 70th Birthday (invited)


54.
Aldehyde-Catalyzed Epoxidation of Unactivated Alkenes with Aqueous Hydrogen Peroxide
I. Triandafillidi, M. G. Kokotou, D. Lotter, C. Sparr,* C. G. Kokotos*
Chem. Sci. 2021, 12, 10191–10196.


TOC

52.
Catalyst Control over Twofold and Higher-Order Stereogenicity by Atroposelective Arene Formation
T. A. Schmidt, C. Sparr*
Acc. Chem. Res. 2021, 54, 2764–2774.


51.
Monitoring Solid-phase Reactions in Self-assembled Monolayers by Surface-enhanced Raman Spectroscopy
D. Scherrer, D. Vogel, U. Drechsler, A. Olziersky, C. Sparr, M. Mayor, E. Lörtscher*
Angew. Chem. Int. Ed. 2021, 60,  17981–17988.


50.
Catalyst control over sixfold stereogenicity
X. Wu,+ R. M. Witzig,+ R. Beaud, C. Fischer, D. Häussinger, C. Sparr*
Nat. Catal. 2021, 4, 457–462.  (+ denotes equal contributions). Preprint deposited on ChemRxiv.

TOC

49.
Organophotocatalytic Aerobic Oxygenation of Phenols in a Visible‐Light Continuous‐Flow Photoreactor
J. Wellauer,+ D. Miladinov,+ T. Buchholz,+ J. Schütz, R. T. Stemmler, J. A. Medlock, W. Bonrath, C. Sparr*
Chem. Eur. J. 202127, 9748–9752. (denotes equal contributions)


48.
Catalyst-Controlled Transannular Polyketide Cyclization Cascades: Selective Folding of Macrocyclic Polyketides
F. C. Raps, V. C. Fäseke, D. Häussinger, C. Sparr*
Angew. Chem. Int. Ed. 2020, 59, 18390–18394.

TOC

47.
Catalytic Cascade Reactions Inspired by Polyketide Biosynthesis
D. Moser, A. Castrogiovanni, D. Lotter, R. M. Witzig, V. C. Fäseke, F. C. Raps, C. Sparr*
Chimia 2020, 74, 699–703. New professors issue


46.
JoyaPhos: An Atropisomeric Teraryl Monophosphine Ligand
A. Castrogiovanni, D. Lotter, F. R. Bissegger, C. Sparr*
Chem.–Eur. J. 2020,  26, 9864–9868. Young chemists special issue


45.
Polyketide Cyclizations for the Synthesis of Polyaromatics
V. C. Fäseke, F. C. Raps, C. Sparr*
Angew. Chem. Int. Ed. 2020,  59, 6975–6983.

TOC

44.
Design and application of aminoacridinium organophotoredox catalysts
B. Zilate, C. Fischer, C. Sparr*
Chem. Commun. 2020,  56, 1767–1775. Invited feature article


43.
Catalyst Repurposing Sequential Catalysis by Harnessing Regenerated Prolinamide Organocatalysts as Transfer Hydrogenation Ligands
F. Bourgeois, J. A. Medlock, W. Bonrath, C. Sparr*
Org. Lett. 2020,  22, 110–115.

TOC

42.
Modulation of Acridinium Organophotoredox Catalysts Guided by Photophysical Studies
C. Fischer,+ C. Kerzig,+ B. Zilate, O. S. Wenger,* C. Sparr*
ACS Catal. 2020,  10, 210–215. (+ denotes equal contributions)

TOC


40.
Shortcuts for Electron‐Transfer through the Secondary Structure of Helical Oligo‐1,2‐naphthylenes
A. Castrogiovanni,+ P. Herr,+ X. Guo, C. Larsen, C. Sparr,* O. S. Wenger*
Chem.–Eur. J. 2019,  25, 16748–16754. (+ denotes equal contributions)

TOC

39.
Scalable Synthesis of Acridinium Catalysts for Photoredox Deuterations
B. Zilate, C. Fischer, L. Schneider, C. Sparr*
Synthesis 2019,  51, 4359–4365. Practical Synthetic Procedure


38.
Atroposelective synthesis of tetra-ortho-substituted biaryls by catalyst-controlled non-canonical polyketide cyclizations
R. M. Witzig, V. C. Fäseke, D. Häussinger, C. Sparr*
Nat. Catal. 2019, 2, 925–930.

Noncanonical

37.
Interface-rich Aqueous Systems for Sustainable Chemical Synthesis
D. Kaldre, F. Gallou, C. Sparr,* M. Parmentier*
Chimia 2019, 73, 714–719. Invited, Sustainable Chemistry Issue


36.
A General Protocol for Robust Sonogashira Reactions in Micellar Medium
M. Jakobi, F. Gallou, C. Sparr,* M. Parmentier*
Helv. Chim. Acta 2019, 102, e1900024.


35.
Author Profile
C. Sparr*
Angew. Chem. Int. Ed. 2019, 58, 944.


34.
Cell Penetration, Herbicidal Activity, and in‐vivo‐Toxicity of Oligo‐Arginine Derivatives and of Novel Guanidinium‐Rich Compounds Derived from the Biopolymer Cyanophycin
M. Grogg, D. Hilvert, M.‐O. Ebert, A. K. Beck, D. Seebach,* F. Kurth, P. S. Dittrich, C. Sparr, S. Wittlin, M. Rottmann, P. Mäser
Helv. Chim. Acta 2018, 101, e1800112.


33.
Configurationally Stable Atropisomeric Acridinium Fluorophores
C. Fischer, C. Sparr*
Synlett 2018, 29, 2176–2180. Special Issue in memoriam Kurt Mislow (invited)


32.
Remote Central-to-Axial Chirality Conversion: Direct Atroposelective Ester to Biaryl Transformation
A. Link, C. Sparr*
Angew. Chem. Int. Ed. 2018, 57, 7136–7139.

""

31.
Catalyst-Controlled Stereodivergent Synthesis of Atropisomeric Multi-Axis Systems
D. Lotter, A. Castrogiovanni, M. Neuburger, C. Sparr*
ACS Cent. Sci. 2018, 4, 656–660.

""

30.
Synthesis of 1,5-Bifunctional Organolithium Reagents by a Double Directed ortho-Metalation: Direct Transformation of Esters into 1,8-Dimethoxy-Acridinium Salts
C. Fischer, C. Sparr*
Tetrahedron 2018, 74, 2436–2440. Sir Derek Barton Centennial Special Issue (invited)


29.
Stereoselective Arene Formation
A. Link, C. Sparr*
Chem. Soc. Rev. 2018, 47, 3804–3815. Emerging Investigator 2018

""

28.
Catalyst-Controlled Stereoselective Synthesis of Atropisomers
B. Zilate, A. Castrogiovanni, C. Sparr*
ACS Catal. 2018, 8, 2981–2988.


27.
Diaryl Magnesium Lithium Alkoxides Derived from (Z)‐4‐(2‐Bromophenyl)but‐3‐en‐1‐ol
D. Lotter, C. Sparr*
in Encyclopedia of Reagents for Organic Synthesis, 2018.


26.
Direct Transformation of Esters into Heterocyclic Fluorophores
C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2018, 57, 2436–2440.

""

25.
Stereoselective Arene-Forming Aldol Condensation: Catalyst-Controlled Synthesis of Axially Chiral Compounds
R. M. Witzig, D. Lotter, V. C. Fäseke, C. Sparr*
Chem. Eur. J. 2017, 23, 12960–12966.


24.
Catalytic Arene-forming Aldol Condensation: Stereoselective Synthesis of Rotationally Restricted Aromatic Compounds
V. C. Fäseke, R. M. Witzig, A. Link, D. Lotter, C. Sparr*
Chimia 2017, 71, 596–599. Werner Prize 2017


23.
A 1,5-Bifunctional Organomagnesium Reagent for the Synthesis of Disubstituted Anthracenes and Anthrones
A. Link, C. Fischer, C. Sparr*
Synthesis 2017, 49, 397–402. Special issue dedicated to Prof. Dieter Enders (invited)

""

22.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Axially Chiral Aromatic Amides
V. C. Fäseke, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 7261–7264.

""

21.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Configurationally Stable Oligo-1,2-naphthylenes
D. Lotter, M. Neuburger, M. Rickhaus, D. Häussinger, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 2920–2923.

""

20.
Direct Transformation of Esters into Arenes with 1,5-Bifunctional Organo­magnesium Reagents
A. Link, C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 12163–12166.

""

19.
Scientific Fireworks to Celebrate the 50th Anniversary of the Bürgenstock Conference
C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 8594–8596.


""

Before Basel

17.
Molecular Design Exploiting a Fluorine gauche Effect as a Stereoelectronic Trigger
Y. P. Rey, L. E. Zimmer, C. Sparr, E.-M. Tanzer, W. B. Schweizer, H. M. Senn,* S. Lakhdar,* R. Gilmour*
Eur. J. Org. Chem. 2014, 1202–1211.


16.
Syntheses, Receptor Bindings, in vivo Stabilities and Biodistributions of DOTA-Neurotensin(8–13) Derivatives Containing β-Amino Acid Residues – A Lesson about the Importance of Animal Experiments
C. Sparr, N. Purkayastha, T. Yoshinari, D. Seebach,* S. Maschauer, O. Prante,* H. Hübner, P. Gmeiner, B. Kolesinska, R. Cescato, B. Waser, J. C. Reubi
Chem. Biodiversity 2013, 10, 2101–2121.


15.
Improved Efficacy of Fosmidomycin against Plasmodium and Mycobacterium Species by Combination with the Cell-Penetrating Peptide Octaarginine
C. Sparr, N. Purkayastha, B. Kolesinska, M. Gengenbacher, B. Amulic, K. Matuschewski, D. Seebach,* F. Kamena*
Antimicrob. Agents Chemother. 2013, 57, 4689–4698.


14.
Synthesis of (–)-Hennoxazole A: Integrating Batch and Flow Chemistry Methods
A. Fernández, Z. G. Levine, M. Baumann, S. Sulzer-Mossé , C. Sparr, S. Schläger, A. Metzger, I. R. Baxendale, S. V. Ley*
Synlett 2013, 514–518.


13.
Exploiting Fluorine Conformational Effects in Organocatalyst Design: The Fluorine-Iminium Ion Gauche Effect
C. Sparr, L. E. Zimmer, R. Gilmour*
in Asymmetric Synthesis II: More Methods and Applications 2012, 117–124.



11.
Preparation and Characterization of New C2- and C1- Symmetric Nitrogen, Oxygen, Phosphorous, and Sulfur Derivatives and Analogs of TADDOL. Part III
D. Seebach,* A. K. Beck, H.-U. Bichsel, A. Pichota, C. Sparr, R. Wünsch, W. B. Schweizer
Helv. Chim. Acta 2012, 95, 1303–1324.


10.
1,2-Oxazine N-Oxides as Catalyst Resting States in Michael Additions of Aldehydes to Nitro Olefins Organocatalyzed by α,α-Diphenylprolinol Trimethylsilyl Ether
D. Seebach,* X. Sun, C. Sparr, M.-O. Ebert, W. B. Schweizer, A. K. Beck
Helv. Chim. Acta 2012, 95, 1064–1078.


9.
Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design
L. E. Zimmer, C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2011, 50, 11860–11871.


""

7.
Theoretical and X-ray Crystallographic Evidence of a Fluorine-Imine Gauche Effect: An Addendum to Dunathan’s Stereo­electronic Hypothesis
C. Sparr, E. Salamanova, W. B. Schweizer, H. M. Senn,* R. Gilmour*
Chem. Eur. J. 2011, 17, 8850–8857.


6.
Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies
C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2010, 49, 6520–6523.


5.
Stereochemical Models for Discussing Additions to α,β-Unsaturated Aldehydes Organocatalyzed by Diarylprolinol or Imidazolidinone Derivatives – Is There an '(E)/(Z)-Dilemma'?
D. Seebach,* R. Gilmour,* U. Groselj, G. Deniau, C. Sparr, M.-O. Ebert, A. K. Beck, L. B. McCusker, D. Sisak, T. Uchimaru
Helv. Chim. Acta 2010, 93, 603–634.



3.
Fluorinated Quinine Alkaloids: Synthesis, X-ray Structure Analysis and Anti­malarial Parasite Chemotherapy
C. Bucher, C. Sparr, W. B. Schweizer, R. Gilmour*
Chem. Eur. J. 2009, 15, 7637–7647.


2.
The Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis
C. Sparr, W. B. Schweizer, H. M. Senn, R. Gilmour*
Angew. Chem. Int. Ed. 2009, 48, 3065–3068.


1.
Synthesis of a Novel γ-Folic Acid-Nτ-Histidine Conjugate Suitable for Labeling with 99mTc and 188Re
C. Sparr, U. Michel, R. E. Marti, C. Müller, R. Schibli, R. Moser, V. Groehn*
Synthesis 2009, 787–792.

Patents

8.
Photooxidation of Phenolic Compounds
W. Bonrath, J. A. Medlock, J. Schütz, J. Wellauer, D. Miladinov, T. Buchholz, C. Sparr
WO2021234080

7.
Photooxidation of 2,3,6-Trimethylphenol
W. Bonrath, J. A. Medlock, J. Schütz, J. Wellauer, D. Miladinov, T. Buchholz, C. Sparr
WO2021234078

6.
Photooxidation of 2,3,5-Trimethylphenol
W. Bonrath, J. A. Medlock, J. Schütz, J. Wellauer, D. Miladinov, T. Buchholz, C. Sparr
WO2021234077

5.
New Transition Metal Catalyst
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2021089482

4.
Stereoselective Synthesis of Enantiomerically-Enriched Pantolactone
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2019228874

3.
Synthesis of a Racemic Mixture of Pantolactone
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2019228873

2.
Small-Molecule Organic Dyes
C. Fischer, C. Sparr
WO2019057451

1.
Folate-Conjugates and Corresponding Metal-Chelate Complexes for Use in Diagnostic Imaging and Radiotherapy
V. Groehn, U. Michel, T. L. Mindt, R. Moser, C. M. Müller, R. Schibli, C. Sparr
WO2008125618