Publications

56.
Catalyst-Controlled Stereoselective Barton–Kellogg Olefination
T. A. Schmidt, C. Sparr*
Angew. Chem. Int. Ed. 2021, 60, accepted. Selected as VIP 

TOC

55.
The Versatility of the Aryne–Imine–Aryne Coupling for the Synthesis of Acridinium Photocatalysts
V. Hutskalova, C. Sparr*
Synlett 2021, 32, accepted. Special Issue Honoring Prof. Shunichi Fukuzumi’s 70th Birthday (invited)


54.
Aldehyde-Catalyzed Epoxidation of Unactivated Alkenes with Aqueous Hydrogen Peroxide
I. Triandafillidi, M. G. Kokotou, D. Lotter, C. Sparr,* C. G. Kokotos*
Chem. Sci. 2021, 12, 10191–10196.


TOC

52.
Catalyst Control over Twofold and Higher-Order Stereogenicity by Atroposelective Arene Formation
T. A. Schmidt, C. Sparr*
Acc. Chem. Res. 2021, 54, 2764–2774.


51.
Monitoring Solid-phase Reactions in Self-assembled Monolayers by Surface-enhanced Raman Spectroscopy
D. Scherrer, D. Vogel, U. Drechsler, A. Olziersky, C. Sparr, M. Mayor, E. Lörtscher*
Angew. Chem. Int. Ed. 2021, 60,  17981–17988.


50.
Catalyst control over sixfold stereogenicity
X. Wu,+ R. M. Witzig,+ R. Beaud, C. Fischer, D. Häussinger, C. Sparr*
Nat. Catal. 2021, 4, 457–462.  (+ denotes equal contributions). Preprint deposited on ChemRxiv.

TOC

49.
Organophotocatalytic Aerobic Oxygenation of Phenols in a Visible‐Light Continuous‐Flow Photoreactor
J. Wellauer,+ D. Miladinov,+ T. Buchholz,+ J. Schütz, R. T. Stemmler, J. A. Medlock, W. Bonrath, C. Sparr*
Chem. Eur. J. 202127, 9748–9752. (denotes equal contributions)


48.
Catalyst-Controlled Transannular Polyketide Cyclization Cascades: Selective Folding of Macrocyclic Polyketides
F. C. Raps, V. C. Fäseke, D. Häussinger, C. Sparr*
Angew. Chem. Int. Ed. 2020, 59, 18390–18394.

TOC

47.
Catalytic Cascade Reactions Inspired by Polyketide Biosynthesis
D. Moser, A. Castrogiovanni, D. Lotter, R. M. Witzig, V. C. Fäseke, F. C. Raps, C. Sparr*
Chimia 2020, 74, 699–703. New professors issue


46.
JoyaPhos: An Atropisomeric Teraryl Monophosphine Ligand
A. Castrogiovanni, D. Lotter, F. R. Bissegger, C. Sparr*
Chem.–Eur. J. 2020,  26, 9864–9868. Young chemists special issue


45.
Polyketide Cyclizations for the Synthesis of Polyaromatics
V. C. Fäseke, F. C. Raps, C. Sparr*
Angew. Chem. Int. Ed. 2020,  59, 6975–6983.

TOC

44.
Design and application of aminoacridinium organophotoredox catalysts
B. Zilate, C. Fischer, C. Sparr*
Chem. Commun. 2020,  56, 1767–1775. Invited feature article


43.
Catalyst Repurposing Sequential Catalysis by Harnessing Regenerated Prolinamide Organocatalysts as Transfer Hydrogenation Ligands
F. Bourgeois, J. A. Medlock, W. Bonrath, C. Sparr*
Org. Lett. 2020,  22, 110–115.

TOC

42.
Modulation of Acridinium Organophotoredox Catalysts Guided by Photophysical Studies
C. Fischer,+ C. Kerzig,+ B. Zilate, O. S. Wenger,* C. Sparr*
ACS Catal. 2020,  10, 210–215. (+ denotes equal contributions)

TOC


40.
Shortcuts for Electron‐Transfer through the Secondary Structure of Helical Oligo‐1,2‐naphthylenes
A. Castrogiovanni,+ P. Herr,+ X. Guo, C. Larsen, C. Sparr,* O. S. Wenger*
Chem.–Eur. J. 2019,  25, 16748–16754. (+ denotes equal contributions)

TOC

39.
Scalable Synthesis of Acridinium Catalysts for Photoredox Deuterations
B. Zilate, C. Fischer, L. Schneider, C. Sparr*
Synthesis 2019,  51, 4359–4365. Practical Synthetic Procedure


38.
Atroposelective synthesis of tetra-ortho-substituted biaryls by catalyst-controlled non-canonical polyketide cyclizations
R. M. Witzig, V. C. Fäseke, D. Häussinger, C. Sparr*
Nat. Catal. 2019, 2, 925–930.

Noncanonical

37.
Interface-rich Aqueous Systems for Sustainable Chemical Synthesis
D. Kaldre, F. Gallou, C. Sparr,* M. Parmentier*
Chimia 2019, 73, 714–719. Invited, Sustainable Chemistry Issue


36.
A General Protocol for Robust Sonogashira Reactions in Micellar Medium
M. Jakobi, F. Gallou, C. Sparr,* M. Parmentier*
Helv. Chim. Acta 2019, 102, e1900024.


35.
Author Profile
C. Sparr*
Angew. Chem. Int. Ed. 2019, 58, 944.


34.
Cell Penetration, Herbicidal Activity, and in‐vivo‐Toxicity of Oligo‐Arginine Derivatives and of Novel Guanidinium‐Rich Compounds Derived from the Biopolymer Cyanophycin
M. Grogg, D. Hilvert, M.‐O. Ebert, A. K. Beck, D. Seebach,* F. Kurth, P. S. Dittrich, C. Sparr, S. Wittlin, M. Rottmann, P. Mäser
Helv. Chim. Acta 2018, 101, e1800112.


33.
Configurationally Stable Atropisomeric Acridinium Fluorophores
C. Fischer, C. Sparr*
Synlett 2018, 29, 2176–2180. Special Issue in memoriam Kurt Mislow (invited)


32.
Remote Central-to-Axial Chirality Conversion: Direct Atroposelective Ester to Biaryl Transformation
A. Link, C. Sparr*
Angew. Chem. Int. Ed. 2018, 57, 7136–7139.

""

31.
Catalyst-Controlled Stereodivergent Synthesis of Atropisomeric Multi-Axis Systems
D. Lotter, A. Castrogiovanni, M. Neuburger, C. Sparr*
ACS Cent. Sci. 2018, 4, 656–660.

""

30.
Synthesis of 1,5-Bifunctional Organolithium Reagents by a Double Directed ortho-Metalation: Direct Transformation of Esters into 1,8-Dimethoxy-Acridinium Salts
C. Fischer, C. Sparr*
Tetrahedron 2018, 74, 2436–2440. Sir Derek Barton Centennial Special Issue (invited)


29.
Stereoselective Arene Formation
A. Link, C. Sparr*
Chem. Soc. Rev. 2018, 47, 3804–3815. Emerging Investigator 2018

""

28.
Catalyst-Controlled Stereoselective Synthesis of Atropisomers
B. Zilate, A. Castrogiovanni, C. Sparr*
ACS Catal. 2018, 8, 2981–2988.


27.
Diaryl Magnesium Lithium Alkoxides Derived from (Z)‐4‐(2‐Bromophenyl)but‐3‐en‐1‐ol
D. Lotter, C. Sparr*
in Encyclopedia of Reagents for Organic Synthesis, 2018.


26.
Direct Transformation of Esters into Heterocyclic Fluorophores
C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2018, 57, 2436–2440.

""

25.
Stereoselective Arene-Forming Aldol Condensation: Catalyst-Controlled Synthesis of Axially Chiral Compounds
R. M. Witzig, D. Lotter, V. C. Fäseke, C. Sparr*
Chem. Eur. J. 2017, 23, 12960–12966.


24.
Catalytic Arene-forming Aldol Condensation: Stereoselective Synthesis of Rotationally Restricted Aromatic Compounds
V. C. Fäseke, R. M. Witzig, A. Link, D. Lotter, C. Sparr*
Chimia 2017, 71, 596–599. Werner Prize 2017


23.
A 1,5-Bifunctional Organomagnesium Reagent for the Synthesis of Disubstituted Anthracenes and Anthrones
A. Link, C. Fischer, C. Sparr*
Synthesis 2017, 49, 397–402. Special issue dedicated to Prof. Dieter Enders (invited)

""

22.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Axially Chiral Aromatic Amides
V. C. Fäseke, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 7261–7264.

""

21.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Configurationally Stable Oligo-1,2-naphthylenes
D. Lotter, M. Neuburger, M. Rickhaus, D. Häussinger, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 2920–2923.

""

20.
Direct Transformation of Esters into Arenes with 1,5-Bifunctional Organo­magnesium Reagents
A. Link, C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 12163–12166.

""

19.
Scientific Fireworks to Celebrate the 50th Anniversary of the Bürgenstock Conference
C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 8594–8596.


""

Before Basel

17.
Molecular Design Exploiting a Fluorine gauche Effect as a Stereoelectronic Trigger
Y. P. Rey, L. E. Zimmer, C. Sparr, E.-M. Tanzer, W. B. Schweizer, H. M. Senn,* S. Lakhdar,* R. Gilmour*
Eur. J. Org. Chem. 2014, 1202–1211.


16.
Syntheses, Receptor Bindings, in vivo Stabilities and Biodistributions of DOTA-Neurotensin(8–13) Derivatives Containing β-Amino Acid Residues – A Lesson about the Importance of Animal Experiments
C. Sparr, N. Purkayastha, T. Yoshinari, D. Seebach,* S. Maschauer, O. Prante,* H. Hübner, P. Gmeiner, B. Kolesinska, R. Cescato, B. Waser, J. C. Reubi
Chem. Biodiversity 2013, 10, 2101–2121.


15.
Improved Efficacy of Fosmidomycin against Plasmodium and Mycobacterium Species by Combination with the Cell-Penetrating Peptide Octaarginine
C. Sparr, N. Purkayastha, B. Kolesinska, M. Gengenbacher, B. Amulic, K. Matuschewski, D. Seebach,* F. Kamena*
Antimicrob. Agents Chemother. 2013, 57, 4689–4698.


14.
Synthesis of (–)-Hennoxazole A: Integrating Batch and Flow Chemistry Methods
A. Fernández, Z. G. Levine, M. Baumann, S. Sulzer-Mossé , C. Sparr, S. Schläger, A. Metzger, I. R. Baxendale, S. V. Ley*
Synlett 2013, 514–518.


13.
Exploiting Fluorine Conformational Effects in Organocatalyst Design: The Fluorine-Iminium Ion Gauche Effect
C. Sparr, L. E. Zimmer, R. Gilmour*
in Asymmetric Synthesis II: More Methods and Applications 2012, 117–124.



11.
Preparation and Characterization of New C2- and C1- Symmetric Nitrogen, Oxygen, Phosphorous, and Sulfur Derivatives and Analogs of TADDOL. Part III
D. Seebach,* A. K. Beck, H.-U. Bichsel, A. Pichota, C. Sparr, R. Wünsch, W. B. Schweizer
Helv. Chim. Acta 2012, 95, 1303–1324.


10.
1,2-Oxazine N-Oxides as Catalyst Resting States in Michael Additions of Aldehydes to Nitro Olefins Organocatalyzed by α,α-Diphenylprolinol Trimethylsilyl Ether
D. Seebach,* X. Sun, C. Sparr, M.-O. Ebert, W. B. Schweizer, A. K. Beck
Helv. Chim. Acta 2012, 95, 1064–1078.


9.
Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design
L. E. Zimmer, C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2011, 50, 11860–11871.


""

7.
Theoretical and X-ray Crystallographic Evidence of a Fluorine-Imine Gauche Effect: An Addendum to Dunathan’s Stereo­electronic Hypothesis
C. Sparr, E. Salamanova, W. B. Schweizer, H. M. Senn,* R. Gilmour*
Chem. Eur. J. 2011, 17, 8850–8857.


6.
Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies
C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2010, 49, 6520–6523.


5.
Stereochemical Models for Discussing Additions to α,β-Unsaturated Aldehydes Organocatalyzed by Diarylprolinol or Imidazolidinone Derivatives – Is There an '(E)/(Z)-Dilemma'?
D. Seebach,* R. Gilmour,* U. Groselj, G. Deniau, C. Sparr, M.-O. Ebert, A. K. Beck, L. B. McCusker, D. Sisak, T. Uchimaru
Helv. Chim. Acta 2010, 93, 603–634.



3.
Fluorinated Quinine Alkaloids: Synthesis, X-ray Structure Analysis and Anti­malarial Parasite Chemotherapy
C. Bucher, C. Sparr, W. B. Schweizer, R. Gilmour*
Chem. Eur. J. 2009, 15, 7637–7647.


2.
The Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis
C. Sparr, W. B. Schweizer, H. M. Senn, R. Gilmour*
Angew. Chem. Int. Ed. 2009, 48, 3065–3068.


1.
Synthesis of a Novel γ-Folic Acid-Nτ-Histidine Conjugate Suitable for Labeling with 99mTc and 188Re
C. Sparr, U. Michel, R. E. Marti, C. Müller, R. Schibli, R. Moser, V. Groehn*
Synthesis 2009, 787–792.

Patents

5.
New Transition Metal Catalyst
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2021089482

4.
Stereoselective Synthesis of Enantiomerically-Enriched Pantolactone
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2019228874

3.
Synthesis of a Racemic Mixture of Pantolactone
W. Bonrath, F. Bourgeois, J. A. Medlock, C. Sparr
WO2019228873

2.
Small-Molecule Organic Dyes
C. Fischer, C. Sparr
WO2019057451

1.
Folate-Conjugates and Corresponding Metal-Chelate Complexes for Use in Diagnostic Imaging and Radiotherapy
V. Groehn, U. Michel, T. L. Mindt, R. Moser, C. M. Müller, R. Schibli, C. Sparr
WO2008125618